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Endocrine Abstracts

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ea0037ep789 | Pituitary: clinical | ECE2015

Acrostart: Spanish retrospective study to determine the timeframe to achieve hormonal normalisation with initial Somatuline Autogel® treatment in acromegaly patients in routine clinical practice

Escola Cristina Alvarez , Moreno Eva Maria Venegas , Arnes Juan Antonio Garcia , Carrera Concepcion Blanco , Azpiroz Monica Marazuela , Moreno Maria Angeles Galvez , Torre Edelmiro Menendez , Pardo Javier Aller , Vert Isabel Salinas , Resmini Eugenia , Vela Elena Maria Torres , Redondo Maria Angeles Gonzalo , Joya Ricardo Vilchez , Novoa Maria Paz de Miguel , Rabinovich Irene Halperin , Fernandez Concepcion Paramo , Alfonso Antonio Miguel Pico , Arroyo Sara , Perez Francesc , Pineda Eva

Introduction: This study aimed to determine the timeframe to achieve hormonal normalization considering dosing patterns of Somatuline Autogel (SOM, lanreotide) used in clinical practice.Methods: From March 2013 to October 2013 clinical data from 62 patients with active acromegaly treated with SOM for &gE;4 months who achieved hormonal control (GH levels <2.5 ng/ml and/or normalised IGF1 on &gE;two evaluations) at 17 Spanish hospitals were collected i...
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ea0032p901 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Efficacy and safety of lanreotide in combination with pegvisomant in clinical practice in patients with active acromegaly with monotherapy failure

Venegas Eva , Lucas Tomas , Marazuela Monica , Cuatrecasas Guillem , Galvez Maria Angeles , Romero Enrique , Morales Francisco , Webb Susan M , Biaggeti Betina , Diaz Juan Jose , Mato Jose Antonio , Vilchez Ricardo , Bernabeu Ignacio , Paja Miguel , Pico Antonio , Domingo Manuel Puig , Soto Alfonso , on behalf of ACROCOMB study group

Introduction: ACROCOMB is a retrospective Spanish Multicenter study, designed to evaluate the efficacy (extent of tumour control) and safety of lanreotide (LAN) treatment combined with pegvisomant (PEG) or cabergoline in acromegalic patients with monotherapy failure.Methods: patients with acromegaly treated with LAN+PEG (45% of ACROCOMB patients) at 44 Spanish Endocrinology Departments were analysed.Results: 40% of patients were ma...
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ea0032p902 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Efficacy and safety of lanreotide in combination with cabergoline in clinical practice in patients with active acromegaly with monotherapy failure

Vilchez Ricardo , Bernabeu Ignacio , Blanco Concepcion , Cordido Fernando , Paja Miguel , Casany Rosa , Fajardo Carmen , Maraver Silvia , Martin Tomas , Lucas Tomas , Arnes Juan Antonio Garcia , Catalina Pablo Fernandez , Icaya Maria Purificacion Martinez de , Sesmilo Gemma , Pico Antonio , Marazuela Monica , Soto Alfonso , Domingo Manuel Puig , on behalf of ACROCOMB study group

Introduction: ACROCOMB, a retrospective Spanish Multicenter study, evaluated the efficacy and safety of lanreotide (LAN) combined with cabergoline (CAB), or pegvisomant in patients with acromegaly.Methods: patients treated with LAN+CAB at 44 Spanish Endocrinology Departments were included.Results: 33% male patients, median age: 50.4 years. Mean time from diagnosis: 5.9±6.9 years. Tumour size at diagnosis: 21.9 mm. 83% of patie...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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